NCBI NCBI DCODE.org Comparative Genomics Developments
NCBI DCODE.org Comparative Genomics Developments
Tools

   ECR Browser
   ECRbase

   Mulan
   zPicture
   eShadow

   DiRE
   SynoR

   Array2BIO

   multiTF
   rVista 2.0

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LINK TO DCODE!

 Whole genome alignments
ECR Browser -- Evolutionary conservation of multiple genomes. Identification and sequence analysis of regulatory elements.
Genome Alignment in ECR Browser -- Align your FASTA nucleotide sequence to a genome of choice.

 Multiple and pairwise sequence alignments
Mulan -- Full multiple sequence alignment. [Interactive conservation profiles, phylogenetic trees, etc.]
zPicture -- Stacked pairwise and multiple sequence alignment.
eShadow -- Phylogenetic shadowing of closely related species.

 Regulation of co-expressed genes
DiRE -- Identification of proximal and Distant Regulatory Elements of co-regulated genes.
SynoR -- Prediction of synonymous regulatory elements in vertebrate genomes.

 Identification of conserved transcription factor binding sites (cTFBS)
Excluding up to 95% false positive TFBS predictions using sequence conservation as a filter.
multiTF -- cTFBS in multiple sequence alignments.
rVista 2.0 -- cTFBS in pairwise alignments.

 Additional resources
Insitu.dcode.org - Xenopus tropicalis in situ database
Reverse complement a nucleotide sequence
Batch sequence retrieval from the UCSC Genome Browser


U.S. National Institutes of Health    U.S. Department of Health and Human Services    USA.gov Dcode.org Comparative Genomics Developments
NLM / NCBI / CBB
The National Institutes of Health (NIH)
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